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Clinical Trials (20 of 29)

A Phase 1 study of AMG 436 in MSI-H/dMMR solid tumors

A safety study testing AMG 436 cancer treatment alone and with other therapies in people with specific types of solid tumors

Status: Recruiting — Phase: Phase 1 — Start:

Conditions: Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)

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A Phase 1/2 study of EIK1005 alone and with pembrolizumab in advanced solid tumors

A study testing a new cancer drug called EIK1005, given alone or combined with pembrolizumab, in people with advanced solid tumors including MSI-H tumors

Status: Recruiting — Phase: Phase 1,Phase 2 — Start:

Conditions: Advanced Solid Tumors, MSI-H or dMMR Advanced Solid Tumors, MSI-H/dMMR Gastric Cancer, MSI-H/dMMR Colorectal Cancer, MSI-H/dMMR Gastroesophageal-junction Cancer, Endometrial Cancer, Mismatch Repair Deficient or MSI-High Solid Tumors

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A Phase 1 study of MOMA-341 in advanced solid tumors

A study evaluating the safety and effectiveness of an investigational drug called MOMA-341 in patients with advanced or metastatic solid tumors

Status: Recruiting — Phase: Phase 1 — Start:

Conditions: Advanced Solid Tumor, Metastatic Solid Tumor, Endometrial Cancer, MSI-H Cancer, Colorectal Cancer, Gastric Cancer, dMMR Cancer

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A Phase 1 study of NST-628 in solid tumors

A study to test the safety and effectiveness of an investigational oral drug, NST-628, in patients with advanced solid tumors

Status: Recruiting — Phase: Phase 1 — Start:

Conditions: Oncology, MEK Mutation, RAF Gene Mutation, Ras (KRAS or NRAS) Gene Mutation, Melanoma, NSCLC, Glioma, Solid Tumor, Adult, MAPK Pathway Gene Mutation

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A Phase 3 study of ivosidenib in chondrosarcoma

A study evaluating the effectiveness of ivosidenib compared to a placebo in treating advanced or metastatic conventional chondrosarcoma

Status: Recruiting — Phase: Phase 3 — Start:

Conditions: Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen

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